Outer-membrane vesicles from Gram-negative bacteria: biogenesis and functions
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چکیده
منابع مشابه
New insight into the application of outer membrane vesicles of Gram-negative bacteria
This review presents a brief outline of our current knowledge of the structure and chemical composition of the outer membrane vesicles (OMVs), originating from the surface of Gram negative bacteria including their outer membrane proteins and lipopolysaccharides. Moreover, the functional roles and applications of OMVs in medical research such as OMV-based vaccines, OMV adjuvants properties, OMV ...
متن کاملOuter membrane protein biogenesis in Gram-negative bacteria
Gram-negative bacteria contain a double membrane which serves for both protection and for providing nutrients for viability. The outermost of these membranes is called the outer membrane (OM), and it contains a host of fully integrated membrane proteins which serve essential functions for the cell, including nutrient uptake, cell adhesion, cell signalling and waste export. For pathogenic strain...
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Bacterial outer membrane vesicles (OMVs) have important biological roles in pathogenesis and intercellular interactions, but a general mechanism of OMV formation is lacking. Here we show that the VacJ/Yrb ABC (ATP-binding cassette) transport system, a proposed phospholipid transporter, is involved in OMV formation. Deletion or repression of VacJ/Yrb increases OMV production in two distantly rel...
متن کاملnew insight into the application of outer membrane vesicles of gram-negative bacteria
this review presents a brief outline of our current knowledge of the structure and chemical composition of the outer membrane vesicles (omvs), originating from the surface of gram negative bacteria including their outer membrane proteins and lipopolysaccharides. moreover, the functional roles and applications of omvs in medical research such as omv-based vaccines, omv adjuvants properties, omv ...
متن کاملThe Outer Membrane of Gram-negative Bacteria and the Cytoplasmic Membrane The Outer Membrane of Gram-Negative Bacteria
The major permeability barrier in any membrane is the lipid bilayer structure, and its barrier property is inversely correlated with its fluidity. Bacteria cannot make this membrane much less fluid or it will start to interfere with the normal functions of the membrane proteins, so some bacteria have constructed an additional structure that surrounds the cell outside the cytoplasmic membrane. A...
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ژورنال
عنوان ژورنال: Nature Reviews Microbiology
سال: 2015
ISSN: 1740-1526,1740-1534
DOI: 10.1038/nrmicro3525